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Four educational tracks

Fatigue and brain fog can
follow different patterns.

The intake identifies your recommended starting track. Each track is built around a distinct symptom pattern — and the same curriculum does not fit all of them.

Take the intake

Four patterns. Explore each one.

You may recognize pieces of yourself in more than one track. The intake identifies your recommended starting track.

Track 01
Gut & Inflammation
Gut Microbiome · Intestinal Permeability · Systemic Inflammation

This track covers the relationship between gut health and systemic energy. When intestinal permeability is disrupted, inflammatory compounds can enter circulation and produce downstream effects on cognition and energy — effects that standard inflammatory markers often don't capture because they're calibrated for disease, not subclinical patterns. The Track 01 curriculum covers what the research says about this pathway and the dietary and lifestyle factors most studied in relation to it.

You may recognize this pattern if…
  • Your mental fog reliably worsens 30–90 minutes after eating
  • Your energy fluctuates across the day without an obvious cause
  • You experience bloating, gas, or digestive discomfort regularly
  • Skin issues — acne, eczema, or rosacea — appear without a clear trigger
  • Joint aches or low-grade muscle soreness that doesn't track with activity
  • Mood instability or low-level anxiety that worsens after certain foods
Curriculum focus
  • Intestinal permeability — what the research says about how it develops
  • The gut-brain axis and bidirectional signaling between gut and cognition
  • Functional inflammatory marker reference ranges vs. standard lab ranges
  • Dietary frameworks studied in relation to reduced systemic inflammation
Inflammatory Marker Review
Track 01
hs-CRP
High-sensitivity C-Reactive Protein
1.8 mg/L
Homocysteine
Amino acid — vascular stress marker
11.2 µmol
Ferritin
Iron storage — also inflammation proxy
22 ng/mL

How the four tracks compare

01Gut & Inflammation
02Hormonal & Thyroid
03Stress & Adrenal
04General Optimization
Primary system
Gut microbiome / systemic inflammation
Thyroid function / T3 conversion
HPA axis / cortisol rhythm
All four systems / foundational lifestyle
Common signals
Post-meal fog, fluctuating energy, digestive symptoms, skin changes
Morning fatigue, cold sensitivity, weight resistance, cognitive slowness
Wired at night, afternoon crash, unrestorative sleep, low stress tolerance
Mixed or unclear pattern, general underperformance, performance-focused
Curriculum focus
Gut-brain axis, inflammatory markers, dietary frameworks
Functional TSH ranges, T3 conversion, thyroid-supporting nutrients
Cortisol Awakening Response, HPA dysregulation, circadian anchors
Nutrition, sleep architecture, movement, stress — all four areas
Lab gap
Standard CRP misses subclinical inflammation
Standard TSH range misses functional subclinical patterns
Cortisol rhythm rarely tested; standard panels miss timing issues
No single marker — diffuse patterns across multiple systems
Consider when…
Symptoms clearly worsen with food, digestion, or inflammatory triggers
Classic low-thyroid symptoms present despite "normal" standard labs
Energy rhythm is reversed — worst in the morning, most alert at night
No single track fits clearly, or you want broad foundational education
01Gut & Inflammation
Primary system
Gut microbiome / systemic inflammation
Common signals
Post-meal fog, fluctuating energy, digestive symptoms, skin changes
Curriculum
Gut-brain axis, inflammatory markers, dietary frameworks
Lab gap
Standard CRP misses subclinical inflammation
Consider when
Symptoms clearly worsen with food or digestive triggers
02Hormonal & Thyroid
Primary system
Thyroid function / T3 conversion
Common signals
Morning fatigue, cold sensitivity, weight resistance, cognitive slowness
Curriculum
Functional TSH ranges, T3 conversion, thyroid-supporting nutrients
Lab gap
Standard TSH range misses functional subclinical patterns
Consider when
Classic low-thyroid symptoms present despite "normal" standard labs
03Stress & Adrenal
Primary system
HPA axis / cortisol rhythm
Common signals
Wired at night, afternoon crash, unrestorative sleep, low stress tolerance
Curriculum
Cortisol Awakening Response, HPA dysregulation, circadian anchors
Lab gap
Cortisol rhythm rarely tested; standard panels miss timing issues
Consider when
Energy rhythm is reversed — worst in the morning, most alert at night
04General Optimization
Primary system
All four systems / foundational lifestyle
Common signals
Mixed or unclear pattern, general underperformance, performance-focused
Curriculum
Nutrition, sleep architecture, movement, stress — all four areas
Lab gap
No single marker — diffuse patterns across multiple systems
Consider when
No single track fits clearly, or you want broad foundational education
Track 01
Gut & Inflammation
Gut Microbiome · Intestinal Permeability · Systemic Inflammation

The Track 01 curriculum covers gut health as a system that affects energy, cognition, and inflammatory burden — and what the research says about the dietary and lifestyle factors most associated with it.

Pattern signals

What this pattern looks like

  • Mental fog that worsens 30–90 minutes after eating
  • Energy that fluctuates unpredictably across the day
  • Bloating, gas, or digestive discomfort
  • Skin issues — acne, eczema, or rosacea without clear cause
  • Joint aches or muscle soreness unrelated to activity
  • Mood instability or low-grade anxiety
  • Food sensitivities that seem to expand over time
Curriculum areas

What this track covers

  • Intestinal permeability and its downstream systemic effects
  • Microbiome composition and diversity patterns in fatigue research
  • Inflammatory markers and functional vs. standard reference ranges
  • The gut-brain axis and bidirectional signaling
  • Dietary frameworks studied in relation to reduced systemic inflammation
  • Probiotic and prebiotic research in energy and cognition
What's included

Track 01 support

  • Track 01 educational video curriculum
  • Gut health protocol framework with research context
  • Elimination and reintroduction phase education
  • HPL Coach calibrated to Track 01 content
  • Access to community members on the same track
  • Optional upgrade to quarterly coaching calls
The mechanism

Why your labs look normal while you feel this way

Standard inflammatory markers (CRP, ESR) are calibrated to detect disease — not the low-grade, subclinical inflammation that research increasingly associates with fatigue and cognitive symptoms. A CRP of 1.8 mg/L reads as "normal" on a standard panel but falls in the elevated range on functional reference standards.

The Track 01 curriculum covers what the research says about these functional reference ranges, how gut permeability contributes to systemic inflammation, and what dietary and lifestyle factors have the most studied associations with improvement.

  • What intestinal permeability means and how it develops
  • How inflammatory signals cross into circulation and reach the brain
  • Why standard reference ranges miss subclinical inflammation
  • What the research says about dietary interventions in this starting pattern
Track 02
Hormonal & Thyroid
Thyroid Function · T3/T4 Conversion · Metabolic Rate

The Track 02 curriculum covers thyroid function, metabolic rate, and the gap between standard lab reference ranges and the functional ranges associated with optimal energy and cognition in the research literature.

Pattern signals

What this pattern looks like

  • Fatigue that does not seem to improve with sleep — and worsens in the morning
  • Cold hands and feet, or consistent low body temperature
  • Weight that resists change despite diet and exercise effort
  • Hair thinning or loss, especially at the outer eyebrows
  • Slow thinking — words that don't come, or difficulty concentrating
  • Constipation or slow digestion
  • Dry skin that doesn't respond to hydration
Curriculum areas

What this track covers

  • Functional reference ranges for TSH, Free T3, and Free T4
  • The T4-to-T3 conversion pathway — and what disrupts it
  • Nutrient cofactors with the strongest research associations with thyroid function
  • The relationship between thyroid function and cortisol patterns
  • Dietary patterns studied in relation to thyroid health
  • How to approach a conversation with your provider about expanded panels
What's included

Track 02 support

  • Track 02 educational video curriculum
  • Thyroid and metabolic protocol framework
  • Lab interpretation education — what to ask your doctor about
  • HPL Coach calibrated to Track 02 content
  • Access to community members on the same track
  • Optional upgrade to quarterly coaching calls
The mechanism

The difference between "normal" and optimal

Standard TSH reference ranges (0.5–4.5 mIU/L) are designed to identify hypothyroidism as a diagnosed condition. Functional wellness research has explored whether symptom burden correlates more closely with a narrower range — around 1.0–2.0 mIU/L — and whether T3 conversion efficiency matters independently of TSH.

The Track 02 curriculum covers what the research says about these distinctions, the nutrient and lifestyle factors most studied in thyroid function, and how to have an informed conversation with your healthcare provider about additional testing.

  • What TSH actually measures — and what it misses
  • The T4-to-T3 conversion process and what disrupts it
  • Which nutrients have the strongest research associations with thyroid function
  • How to approach a conversation with your doctor about expanded panels
Track 03
Stress & Adrenal
HPA Axis · Cortisol Rhythm · Circadian Regulation

The Track 03 curriculum covers cortisol timing and HPA axis regulation — specifically what the research says about how the cortisol curve becomes disrupted under sustained stress, and what lifestyle factors are most studied in supporting its correction.

Pattern signals

What this pattern looks like

  • Tired during the day, alert at night — reversed energy rhythm
  • Afternoon energy crash, typically between 1–3pm
  • Sleep that doesn't restore — wake up exhausted despite hours in bed
  • Low tolerance for stress — what used to be manageable now feels overwhelming
  • Anxiety or a persistent sense of low-level dread
  • Cravings for salt or sugar, especially in the afternoon
  • Slow recovery from illness or physical exertion
Curriculum areas

What this track covers

  • The HPA axis — how it governs the cortisol response cycle
  • Cortisol Awakening Response (CAR) and what a dysregulated curve looks like
  • How chronic stress rewires the HPA set point over time
  • Sleep architecture and cortisol — why rhythm disruption prevents deep rest
  • Adaptogens and stress-modulating compounds studied in HPA dysregulation
  • Circadian rhythm research and light/dark cycle interventions
What's included

Track 03 support

  • Track 03 educational video curriculum
  • Adrenal and stress protocol framework
  • Cortisol rhythm education and intervention research
  • HPL Coach calibrated to Track 03 content
  • Access to community members on the same track
  • Optional upgrade to quarterly coaching calls
The mechanism

It's not about how much cortisol you make — it's about when

A healthy cortisol curve peaks sharply within 30–45 minutes of waking (the Cortisol Awakening Response), then declines steadily through the day, reaching its lowest point around midnight. Under chronic stress, this curve flattens, inverts, or shifts — meaning cortisol is elevated at night when the body needs to wind down, and low in the morning when it needs to function.

The Track 03 curriculum covers what research says about HPA axis dysregulation, the lifestyle factors most studied in cortisol rhythm support, and why adaptogenic compounds have attracted significant research interest in this starting pattern.

  • What a dysregulated cortisol curve looks like vs. a functional one
  • How sleep deprivation and cortisol dysregulation form a reinforcing loop
  • Light exposure, meal timing, and other circadian anchors studied in HPA support
  • Adaptogen research — what the evidence says and where it's limited
Track 04
General Optimization
All Four Systems · Foundational Lifestyle · Mixed Patterns

The Track 04 curriculum covers all four system areas — gut health, thyroid function, cortisol rhythm, and foundational lifestyle factors — making it the recommended starting track when symptom patterns are mixed, unclear, or performance-focused without a specific dominant signal.

Pattern signals

What this pattern looks like

  • General fatigue without a dominant or clear pattern
  • Inconsistent energy — good days and bad days with no obvious cause
  • Baseline cognitive performance that feels below potential
  • Sleep that feels adequate but not restorative
  • Desire to perform better across work, fitness, or cognitive tasks
  • Multiple signals spread across systems without one clear driver
  • Preventive — wanting to address fatigue before it becomes more defined
Curriculum areas

What this track covers

  • Foundational nutrition research for energy and cognitive performance
  • Sleep architecture, slow-wave sleep, and recovery optimization
  • Movement and exercise research as mitochondrial support
  • Stress resilience and nervous system regulation
  • Circadian biology and chronotype-based performance windows
  • Overview of all four system tracks — broad-spectrum education
What's included

Track 04 support

  • Track 04 educational video curriculum — all four system areas
  • General Optimization protocol framework
  • Lifestyle, sleep, and nutrition research modules
  • HPL Coach calibrated to Track 04 content
  • Access to community members on the same track
  • Optional upgrade to quarterly coaching calls
The mechanism

The four pillars that determine baseline performance

When no single system is clearly dominant, the most effective educational approach covers the four areas with the highest research-backed associations with energy and cognitive performance: nutrition quality, sleep architecture, movement patterns, and stress regulation.

The research is clear that foundational factors compound — addressing one in isolation rarely produces reliable improvement in people with diffuse or mixed starting patterns. The Track 04 curriculum is built around the evidence for all four areas together.

  • How mitochondrial efficiency is affected by nutrition, sleep, and movement together
  • Why lifestyle factors compound — and why addressing one in isolation rarely works
  • The research case for all-four-system education in mixed-pattern fatigue
  • What a performance-focused approach looks like vs. a symptom-focused one

HPL tracks are educational starting points — not medical categories or diagnoses. Reading through the four tracks may produce a moment of recognition, but the intake questionnaire is the tool designed to identify your recommended starting track based on your full symptom pattern and history.

The intake identifies a starting track. It does not diagnose a condition, and it is not reviewed by Dr. Hanes as individual clinical care. Your starting track can be updated if your pattern shifts over time.

HPL Coach and the HPL curriculum do not provide medical advice. Nothing on this page or in the program constitutes diagnosis, treatment, or a substitute for professional medical care. Always consult a qualified healthcare provider for medical decisions.

Find your starting track

A structured path from
scattered signals.

The intake identifies your recommended starting track. Fifteen minutes of questions about your symptom pattern, timing, and history — and a curriculum sequenced for what it finds.

Educational, not medical  ·  Starting pattern, not a diagnosis  ·  Individual results vary